Photosensitivity and St.Johns wort Jay__0__0. The most common adverse effects are gastrointestinal symptoms, dizziness/confusion, and tiredness/sedation. The most commonly reported adverse effects from St. John's wort include gastrointestinal symptoms, allergic reactions, dizziness, confusion, drowsiness, photosensitivity, and dry mouth. I am 33 and grew up on the beach and never had this before in my life. Although St. John’s wort needs a fair bit of light to thrive, it does best in partial sun. Rational Phytotherapy: A Physician’s Guide to Herbal Medicine. The species name “perforatum” refers to the fact that the leaves of the plant are “perforated” or appear to have tiny holes which can only be seen on close inspection. Some sysop accidentally sent me posts from alt.flame.mushroom.mushroom.mushroom for the last few days instead of the Herb List! There was no correlation between total hypericin plasma concentrations and photosensitivity. Anyone know a study that indicates photosensitivity in humans do to Hypericum? It should be kept in mind that UV light is a risk factor for cataracts on its own.15 Additionally, antioxidant intake appears to have a protective effect. He casually announced that he had been taking a pharmaceutical anti-depressant for nearly a decade...I hadn't even noticed. The photosensitizing effects of topical hypericum also have been studied and appear to be much more mild than the effects of oral or intravenous administration. Alas, for I wonder...when there are only small populations left in the area...will St John become a rare and protected plant?????? I wanted to start out slow on it, so I only take one pill @ 300 mg. per day. There is really only one cause for St John’s wort poisoning and that cause is simply the ingestion of the plant by the horse. Gulick RM, et al. You must have JavaScript enabled to enjoy a limited number of articles over the next 360 days. SSI sensitivity was the same in both groups after hypericum treatment. The medications omeprazole (Prilosec) and lansoprazole (Prevacid) may also increase the tendency of St. John's wort to cause photosensitivity. I suspected that incidents of phototox could be found somewhere, just couldn't come up with them. 1121-1122. In the multiple dose segment, 50 volunteers received 600 mg hypericum extract tid (twice the normal recommended dose) with a daily dose of 5.6 mg of total hypericin. Photosensitive reactions vary among individuals using St. John’s wort and are typically seen when large internal doses of the plant are used; however, it is generally suggested that anyone using St. John’s wort use caution in the sun (Hoffmann, 2003). I actually took a botany class at UC Berkeley (CA Native Plantlife) in which one of the wonderous professors suggested covering large areas of the Central Valley with black plastic in order to eradicate St. John's Wort. Hello! So ideally...the Wort would take away the highs and lows and make the emotional rollercoaster of todays hectic society more even. >I am much in support of bioregionalist solutions and actually got my B.S. Schempp CM, et al. From: Howie Brounstein . Bernd et al attempted to estimate the potential risk of phototoxic skin damage with St. John’s wort by comparing the phototoxic agent psoralens to hypericin in cultivated human keratinocyte cultures.12 A concentration- and light-dependent decrease in DNA synthesis (determined by the incorporation rate of bromodeoxyuridine) was noted with very high hypericin concentrations (> 50 mcg/mL) combined with UVA or visible light (but not UVB) radiation. Like the Wandering Homeopath, traveling the world seeking provings (you mean you haven't heard THAT legend? Other drugs that have the same active ingredients (e.g. Increased sensitivity to sunlight (photosensitivity) 10. St John's wort does appear to have a more favourable short‐term safety profile than do standard antidepressants, a factor that is likely to be important in patients continuing to take medication. In 1999, alarm spread regarding the association of St. John’s wort with the development of cataracts. Although hypericin clearly is linked to photosensitivity reactions, pseudohypericin also may be involved. St. John’s wort tea or tincture is a popular remedy for burns, sunburns, wounds, bruises, sores, insect bites, and cramps. St John's Wort and photosensitivity (4 Posts) Add message | Report. As most herbs, only using Hypericum for its anti-anxiety effects is to ignore the subtle shades and colors it causes as it moves INTO, THROUGH and OUT of the body. I set it free! With many of these kinds of problems.....you may not be able to tell if it's working...especially since you started taking it and you feel great...I mean really good...as you swing up into a manic phase and over one edge or the other. Accessed December 1, 2000. St John’s wort may also impact on the breakdown of other drugs by I started taking St. Johns wort for depression over the winter. Hautarzt 1997;48:249-52. A calming herb that grows all over disturbed areas...hmmmmm. at Berkeley around Bioregional solutions! Brockmoller J, et al. Misinformed press reports warned that people taking St. John’s wort on a regular basis could put themselves at risk if they were exposed to bright light.13 These reports arose as a result of work carried out by Schey et al.14 This was an vitro study in which alpha-crystallins isolated from calf lenses were incubated in 50 micromolar hypericin (approximately 1,000 times therapeutic plasma concentrations) in the presence and absence of light. That is one reason why, while many are studying Chinese, or TCM, herbalism, I have chosen to pursue the study of Western Phytotherapy. >But of interest to me was the notion that sunlight increased the Wort's anti-viral effects........that sun again......somehow..in some mysterious way linked to this plant and it's effects. Since he suffered from some mild hereditary neuropeptide imbalances that showed up as a fairly classic long-cycle bipolarity, he was quite taken with the use of the fresh tincture of both Hypericum perf. 200-203. Two case reports of photoactivated toxicity with St. John’s wort have been reported. 40-43/56. Hypericum is well tolerated with an incidence of adverse reactions similar to placebo. Peter wrote a book in 1978 called REINHABITING A SEPARATE COUNTRY: A BIOREGIONAL ANTHOLOGY OF NORTHERN CALIFORNIA (Planet Drum Foundation Publishers). He had been bombed every day for a decade and I hadn't noticed. John’s wort is also associated with photosensitivity and skin rash. Antihistamines and antiinflammorty drugs may help in early cases. After steady-state administration (300 mg/d tid for seven days) the mean serum level of hypericins was 12.5 mcg/mL. I have found that they have really helped, not so anxious, no panic attacks, feel brighter and my RLS is only a few days a month now. A 35-year-old woman who took St. John’s wort (ground whole herb, 500 mg/d) for mild depression developed subacute polyneuropathy after sun exposure.3 One month after starting St. John’s wort, the patient developed stinging pain in sun-exposed areas, including the face and hands; she noted mild pain that appeared to be worsened by sun exposure. Spread regarding the association of st john's wort photosensitivity John 's wort in pharmacy school we were told to St... Grew up on the skin milk and may cause unwanted effects in small! Message | report sunlight.... the herbs anti-viral effect dropped markedly of,... 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