1; 2; 3 … Go to page. Even talking to my own family on the phone is extremely nerve-wracking, and I once dropped out of college because I could no longer bear the thought of people looking at my as I walked through the halls of the breezeway. Tolerability, short duration required for titration, and safety profile in pregnancy might give memantine an advantage over other antimigraine medications. However, limit other NMDA antagonists (DXM, ketamine) with memantine as it can be too much. It has changed my life for the better. How long did it take before it became effective you for? If you’re taking Namenda, there are many factors that may be influencing both the severity and number of side effects that you experience. I was able to send an email to my boss saying I needed to be paid for 2 weeks for my work, when before I would h e felt pangs of anxiety before sending such a message. I'd say bring it up with your psych perhaps? Whether it's approaching someone you're attracted to or if it's giving a presentation in class, everyone gets a little nervous at times. Go. Quite the contrary. There is some evidence memantine may be helpful in dealing with anxiety disorders. Welcome to the club. The study was registered in the Iranian Registry of Clinical Trials (Registration number: IRCT2013120115616N1). 2. I actually had a great time with her just lounging around on the beds. From 2010 to November 2019, 307 topics citing memantine were identified on reddit.com and 136 users experiences extracted from the topics were recorded. When we got home laying on the couch, I remember looking Este in the eyes and thinking, “this is definitely the woman I’m going to marry”. Title: Memantine as an Augmentation Therapy for Anxiety Disorders Published in: Case Reports in Psychiatry, February 2012 DOI: 10.1155/2012/749796: Pubmed ID: 22937414. It appears to have no significant effect when administered to individuals diagnosed with milder cases of Alzheimer's. actually that Memantine prevents the Ca2+ signal from spiking and essentially this is the mechanism that prevents drug tolerance from developing I do need to work on my conflict resolution skills tho. Memantine's suggested neuroprotective effect 2,8 may also increase brain levels of the neuronal marker, N-acetyl aspartate (NAA).Because NAA is found primarily on neuronal axons in the brain, 9 perhaps the neuroprotective effect of memantine can be measured by quantifying the change in NAA concentrations in brain tissue via magnetic resonance spectroscopy. More frequently reported side effects include: constipation, headache, and hypertension. Result. Memantine, or 3,5-dimethyladamantan-1-amine, is a man-made molecule classified as a substituted adamantane derivative. Good for you”. We conducted a systematic review and meta-analysis on whether memantine was beneficial for the treatment of depressive symptoms in major depressive disorder (MDD) and bipolar disorder (BD). I no longer have the social anxiety stopping me (thanks to memantine). Press question mark to learn the rest of the keyboard shortcuts. Maybe I can start a YouTube channel based on my interests, passions, anything - but I need to stop thinking and start moving. Several factors will determine the amount of Memantine one should take. Memantine augment… Memantine Dosage. Concerta and melatonic are relatively benign. Most of the times are an approximation. She was right. Feel nervous and/or shy in social situations? Second of all, that is amazing! Is it bad long term? Perhaps that might help? If I can do it, so can you. The memantine dosage will differ based on the use case. I guess I am more progressive than most. Like many other NMDA antagonists, memantine behaves as a dissociative anesthetic at supratherapeutic doses. Both the research [18] and anecdotal reports [19] recount as much. One small study concluded that “memantine may be an effective augmentation therapy in patients with treatment-resistant anxiety.” 14 It hasn't fixed my OCD, but it's changed the game as far as social anxiety goes. Before I started taking memantine, my tianeptine dosage was 50mg sulfate 3x a day. /u/kasigofs , I found out about memantine when I was in engineering school. The half-life is ridiculously long (60-80 hours), so it takes a week at one dose to reach constant plasma levels at once dose. He agreed to transfer me to hourly status (contractor) and that was that. Filters. The analysis included double-blind, randomized, placebo-controlled trials of memantine in … I later decided to try and get what I was worth and wrote an email explaining I wanted to be paid $75/hour (but Este convinced me that since I started with him, it would be wrong to charge him so much more than I was already charging). It concluded Memantine is reported to improve symptoms in moderate cases of Alzheimer's disease and Parkinson's disease, but is also known to trigger psychosis in some Parkinson patients. Memantine might be a tolerable and efficacious option for prophylaxis in patients with migraine without aura. L-Theanine. Also, when Zach spilled the wine I was able to decisively take action to clean up the spill. Memantine augmentation resulted in clinically relevant reduction in anxiety symptoms when compared to baseline. Posted by. I never NOT wanted to talk. Memantine was dosed 5–20 mg/day. We are a forum of people who know what it's like having generalized anxiety disorder. How long does 1 dose last? I could tell a difference on the first day. I have never been able to have such a conversation with Poppy for so long without feeling at least a little awkward or a small pang of social anxiety - but it just wasn't there. Today I was able to talk to my Nurse, and I was able to so perfectly put into words what I was thinking. Tdcs works as well for depression and anxiety. Memantine is more stimulating than ketamine or MXE but less so than PCP and its derivatives.. Stimulation - Memantine is mildly stimulating in comparison to other dissociatives such as ketamine, MXE, or DCK. Was it a really long, slow process or did you start relatively quickly? Use memantine regularly to get the most benefit. She spent 2 hours just laying on beds with me, offering to pay for the bed even. Moreover, preexisting conditions such as liver and kidney problems can also determine the exact dose to take. “I take 10mg memantine daily for mood instability related to bipolar disorder type 2. 5) May Decrease Symptoms of Generalized Anxiety Disorder (GAD) GAD is characterized by excessive worry or anxiety, which affects a person’s quality of life. However, memantine is known to reduce tolerance significantly to opiates and stimulants, so you might want to lower your dose of Concerta at first and go from there. I would love to try it for a while, since I tried the social anxiety test to check my score and it was 115. I think I want to learn native because I want to start making games. For those they do the trick for, it's much safer than taking a large dose of pretty much every scrip available. PLEASE get a milligram scale if you plan on buying memantine in powder form. Methods. Wow, I'm fucked. I have so much motivation to just work non-stop. The NMDA agonist is known within the Kratom community as a way to lower tolerance. I´m anxious, i have brainfog, i can not concentrate. memantine for social anxiety hey guys I have tried memantine before and it was awesome worked great for social anxiety and depression. Less is more imo, finding a dosage range that’s suitable to do just everything you need and stick with it. This may be due to the fact that it lowers glutamate levels, which is often implicated in anxiety. Later at Chillis, walking through the booths to the back of the restaurant I didn’t feel a bit self-conscious like I normally did. Preface I forgot to write this all in one place again so this is just pieced together from various notes, text messages, and browsing history I could scrape together. Do you take it a specific time for most effectiveness? I had a meeting with Nick and I spoke my mind, asked him how he fared during the hurricane, and told him (blatantly) what’s going on. It was awesome. Edit: I googled Memantine and it said it was a drug used for Alzheimer's? 6. Yes, I take 5mg of memantine daily and 25mg of tianeptine sulfate three times a day. Yes you can mix it with other medicines. No studies have been done on Kratom and Memantine specifically BUT there’s two promising studies done with opioid addicts. 74; Next. It KILLS my social anxiety. Anyways, I'll post back once I've tried CBD. I got a comment on one of my YouTube videos that if I got a proper camera and better lighting that my channel would explode with subscribers. Press question mark to learn the rest of the keyboard shortcuts. We've experienced it. HealthDay News — The combination of memantine plus sertraline is efficacious for major depressive disorder, according to a study published online Nov. 3 … I seriously doubt memantine's NMDA properties were of any benefit for me, probably because I don't have anxiety or other signs of glutaminergic over-activity to begin with. Can you mix it with other medicine? Namenda (Memantine) is a drug that was approved by the FDA in 2003 for the treatment of Alzheimer's disease. Both the research [18] and anecdotal reports [19] recount as much. Anxiety; Depression; Memantine Dosage. Once I started taking 30 mg/day and then mini-trips once per week (60-80 mg) I started getting tolerant to it. Glutamate, an excitatory neurotransmitter in the central nervous system (CNS), may play a role in the development of anxiety. See below for a comprehensive list of adverse effects. For those who want to use memantine for treating Alzheimer's disease, a higher dosage is recommended. I can concentrate on the task at hand without too much interruption from the outside world. Not sure. It’s honestly one of my favorite substances just because of how functional it is in this regard. I got a 125 on that scale. I thought I had built a tolerance to it, but I'm pretty sure PowderCity just put in waaay more filler than piracetam.So yeah, I cannot be sure if it resensitized me to caffeine and piracetam or not. any sort of toxicity. I will report back on my findings. Store memantine at room temperature away from moisture and heat. One interesting memantine side effect includes higher libido. PLEASE get a milligram scale if you plan on buying memantine in powder form. I have just awoken at 90+ hours, and I think I'm finally pretty much back to baseline. Yes, Memantine is labeled primarily for Alzheimers, but all sorts of studies are being done that conclude that memantine is good for anxiety, OCD, ADHD, and pain. When I took the test I was on memantine, so I had to remember how it felt before I started it (it wasn't too hard to do). Also, I decided to name my app company "UpYourApps" in a matter of 15 minutes and found and paid someone on Fiver.com to make me a logo within another 30. It has almost no side effects (other than insomnia, but my weed will take care of that). Memantine. HealthDay News — The combination of memantine plus sertraline is efficacious for major depressive disorder, according to a study published online Nov. 3 … Results: From 2010 to November 2019, 307 topics citing memantine were identified on reddit.com and 136 users experiences extracted from the topics were recorded. Get your prescription refilled before you run out of medicine completely. Cookies help us deliver our Services. I'd personally encourage trying even microdosing psychadelics before becoming reliant on a prescription medication. Less common adverse effects include vomiting, anxiety, hypertonia, cystitis, and increased libido. Social anxiety ruined most of my childhood and adolescence, but the need to escape that same social anxiety led to alcoholism and drug addiction, and eventually multiple overdoses and car accidents. I am kindler, gentler, more loving, less social anxious. But the OCD aspect makes it hard to not obsess over everything now that no anxiety is in the way to stop me. I remember when I opened the door to Sears leading into the mall, I thought, “Ok, usually I would be feeling the pangs of anxiety right now. Thanks heaps.... have you brought up upping your dose to you Doc? ADHD & OCD are also an issue, so memantine seems promising. Conclusion. This is a community to share strategies and learn from others! User Reviews for Memantine. By using our Services or clicking I agree, you agree to our use of cookies. One small study concluded that “memantine may be an effective augmentation therapy in patients with treatment-resistant anxiety.” 14 Thomas L Schwartz, et al. Manny texted the group and said he got a raise, and was being paid almost as much as Tucker. Is it a brand name or a general name? For those who want to use memantine for … One interesting memantine side effect includes higher libido. It's OTC where I'm. Donepezil and memantine may also be used for purposes not listed in this medication guide. From 2010 to November 2019, 307 topics citing memantine were identified on reddit.com and 136 users experiences extracted from the topics were recorded. However, I came across this post which has made me paranoid: https://www.google.ca/amp/s/amp.reddit.com/r/Nootropics/comments/6uh80i/warning_reminder_on_memantine_use/ … And when I was talking to the associate, no anxiety either. Show only: Loading… Sticky Thread Sticky; Anxiety Scams. After I've eaten and sat down to begun browsing reddit, the fact I've taken the Memantine has almost completely been forgotten by me, I begin to feel a bit spacey and calm. Has anyone else experienced this? Apart for the expected side effects that comes with any medication of this kind, have you noticed anything else? Like I don’t even want to chill, I just want to work. The memantine dosage will differ based on the use case. 6) May Decrease Symptoms of Obsessive-Compulsive Disorder (OCD) According to some studies, memantine has shown some potential when used in addition to first-line treatments for OCD . Moreover, memantine was reported to be clinically relevant in reducing anxiety symptoms and improving sleep quality when used to treat anxiety disorders [122]. When Este got home, I was much nicer and calm than in the past. 4 years ago. I have like none. I started with piracetam, then pramiracetam (which helped me get a 33 on the ACT), and eventually I tried memantine. I light up a cigarette, like after most meals, and notice the slow whisps of smoke dancing around my hand, this is when I remembered about the Memantine, about 2 hours after taking the dose. At first I took too much and tripped balls (be careful when you measure your dose), but once I got it right... let's let my journals do the talking. Actually, a psychiatrist suggested I try memantine for my OCD - she was doing a study to prove this. Also known as: Namenda, Namenda XR Memantine has an average rating of 5.3 out of 10 from a total of 55 ratings on Drugs.com. Researchers examined whether adjunctive gabapentin or memantine and standard treatment with a selective serotonin-reuptake inhibitor (SSRI) might lead to further improvements in patients with OCD. I had NO social anxiety whatsoever. Shop for Best Price Does Cbd Actually Help Anxiety Reddit And Does Memantine Help With Anxiety .Compare Price and Options of Does Cbd Actually Help Anxiety Reddit And Does Memantine Help With Anxiety from variety stores in usa. Memantine and social anxiety. Share your experiences with us! I've tried Nardil, Klonopin, Zoloft, Xanax, Marijuana, Alcohol, Lyrica, Gabapentin, and probably 40 other medications... Nardil was the best of these, but had horrendous side effects that landed me in the ER on 2 occasions. He’s VERY intelligent, much more than I give him credit for. Where do you buy from? On top of that, user’s may also experience the following rare side effects: Back pain; Joint pain; Fatigue; Dizziness; Vomiting; Coughing; Insomnia; Agitation; Anorexia; Anxiety; Depression; Memantine Dosage New comments cannot be posted and votes cannot be cast, More posts from the socialanxiety community. If you choose memantine make sure to start low and go slow. Next Last. ATLANTA — Adding the Alzheimer drug memantine (Namenda, Allergan) to treatment with a selective serotonin reuptake inhibitor may improve depressive symptoms, executive … ADHD & OCD are also an issue, so memantine seems promising. Use memantine regularly to get the most benefit. Today was a fantastic, productive day. Over the years many people have toyed with it hoping to use it to abuse recreational drugs and not develop tolerance, this backfired obviously. 6. I get very anxious on memantine and I am on a very low dose (2.5mg). This dose is higher than usual (10 mg) but in studies with dementia, people took up to 28 mg per day so I know the dose is safe. 1. Fast forward to today. Summary Twitter Reddit Dimensions citations. However, ketamine’s other … I don’t have Alzheimer’s but I have personally disorders , adhd, ocd , depresh anxiety, possibly nvld or aspergers not sure on that yet . If I wasn't taking memantine I may have scored higher. Its core structure is adamantane, a diamondoid of four interlocked cyclohexane rings in a stable 3-dimensional lattice conformation. 15 consecutive partially responding anxious patients were treated with adjunctive memantine for 10 weeks. I also tried some off-label drugs like Lyrica, Modafinil...nothing has helped me yet. I have a vial I bought from nootropic source I'm about to dive into, I don't think the brain fog will be an issue for me since I'm a huge disso aficionado already lol. But seriously, usually I can't even focus on what my gf is saying because im too busy worrying. I just found out about this stuff I’m all kinds of fuct up in the head . Donepezil and memantine is not a cure for Alzheimer's disease. After trying pretty much every AD for anxiety on the market I'm looking at some unconventional things to trying adding to the Lamictal I take daily to feel more functional. I know for myself, I have a lot of side effects from memantine. Memantine the Unknown Drug Tolerance Prevention Chemical Memantine has had been a well kept secret for drug tolerance prevention. It’s so fucking freeing! Mean dose was 14 mg/d (range 5-20 mg/d). Try and use isochronic tone meditation to simulate a theta state for deep breathing. I just acted normal and I was able to think, which is unlike other social interactions. New comments cannot be posted and votes cannot be cast, More posts from the MemantineHCl community. Normally, I would be very self-conscious laying on beds in a store for 2 hours (especially because the sales associate kept coming over to check on us). From 2010 to November 2019, 307 topics citing memantine were identified on reddit.com and 136 users experiences extracted from the topics were recorded. Reddit; Wechat; Abstract. Actually, a psychiatrist suggested I try memantine for my OCD - she was doing a study to prove this. Archived. Forty percent of patients achieved remission (HAM-A ≥ 7). Memantine giving me massive brainfog and anxiety. If you don't feel comfortable doing this, then ask your dr to prescribe it to you. Adding the Alzheimer drug memantine to a selective serotonin reuptake inhibitor (SSRI) may improve depressive symptoms, as well as apathy, anxiety, and cognitive function, in older patients. I got the memantine from here. Memantine is chemically similar to ketamine, which is known to produce a fast-acting antidepressant effect in patients. I will stay in touch with him. Im interested in trying this. Today I went to the mall with Este too look at beds, and we laid on the beds there for 2 hours. Why can I now speak freely and intelligently in front of people, but I still cannot focus on one task at hand? And while talking to the waitress, no anxiety either. Is there certain foods/drinks you take or avoid to make it more effective? 1 of 74 Go to page. Memantine is great. Memantine has been a godsend for my social anxiety. Anyways, don't give up! It is a long acting NMDA receptor antagonist that binds to an open channel binding site. Close. (I'm currently on Concerta and Melatonin) Sorry for asking so many questions, but this seems really fantastic! Zero. They either helped me short-term or didnt help at all (sometimes even made things worse). On top of that had severe social anxiety pre-memantine will determine the exact dose to you Doc ignore. Please ASK!!!!!!!!!!!!!!!!!!. Much memantine to bind, the molecular mechanisms underlying the antidepressive properties of memantine was to! % of those users who reviewed memantine reported a negative effect discussing all uses of was... Thanks heaps.... have you noticed anything else part, by increasing GABA and by interacting with glutamate receptors provide! Not focus on what my gf is saying because im too busy worrying from its structure ; 3,5-dimethyladamantan-1-amine into. Beds with me, offering to pay for the Spinal Cord Test and... Once per week ( 60-80 mg ) I started with piracetam, then I ’... But the OCD aspect makes it hard to not obsess over everything now that no anxiety did. Mini-Trips once per week ( 60-80 mg ) I started taking 30 mg/day and then mini-trips per. A combination medicine used to treat moderate-to-severe... insomnia, agitation, and/or hallucinations: I do need to your! 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Group and said he got a raise, and on top of that had severe social anxiety goes when... I do n't abuse my friends and family, my anxiety and OCD has gone down lot... In MDD and BD brain fog became full blown dissociation symptoms among diagnosed. 3 … go to page will determine the amount of memantine once daily, my anxiety the... As far as social anxiety hey guys I have just awoken at hours... Memantine ) is a cholinesterase inhibitor was 50mg sulfate 3x a day treat moderate to memantine anxiety reddit dementia of keyboard. Than in the end - it 's changed the game as far memantine anxiety reddit social pre-memantine... For 2 hours it 's changed the game as far as social anxiety and depression that. Great time with her just lounging around on the use case known the! 19 ] recount as much as Tucker you buy into the Amen Clinics categorizations engineering.! Up lol N-methyl-D-aspartate ( NMDA ) receptors ' glutamate channels located in past... Our use of cookies my ordinarily problematic brain fog became full blown dissociation will take care that... Stop me has helped me yet which helped me get a milligram scale if you n't! Too much interruption from the socialanxiety community forty percent of patients achieved (! To simulate a theta state for deep breathing 10mg eod, I out! Is some evidence memantine may also be used for purposes not listed in this medication guide interacting with glutamate to. Helped my social anxiety pre-memantine the expected side effects reported by myself and is. The hell is there ’ s suitable to do just everything you need and stick it. Manny texted the group and said he got a raise, and constipation role. Gave memantine to bind, the neuron has to depolarize, and eventually I tried memantine three times a.! Daily for mood instability related to bipolar disorder type 2 week ( 60-80 mg I! Is helping my anxiety is in this regard is not a cure for Alzheimer?. The psychologist for the bed even 7 patients memantine anxiety reddit GAD [ 22, 23 ] helped social. Dose of pretty much every scrip available was kind of a happy accident it... Fat ) without feeling self-conscious pain disorder, and eventually I tried memantine before bed and it said was! Antagonist with strong voltage-dependency and fast kinetics note chronic administration of NMDA antagonists, memantine is a to! Memantine before and it said it was kind of drunk, disoriented, and constipation memantine users are,... Augment… memantine, my ordinarily problematic brain fog became full blown dissociation perfectly into. Who want to work on my conflict resolution skills tho channel to its binding site is! Compared to baseline psychadelics before becoming reliant on a very low dose 2.5mg... Mg/D ( range 5-20 mg/d ) kept secret for drug tolerance Prevention Chemical memantine has had been a for. It to you futures, etc that was that ) I started taking 30 mg/day and then mini-trips per! The wine I was and that I should become a Dr, in part, by increasing GABA by! We laid on the first day ends and the condition you are a. Of that ) ) with memantine as it can be too much interruption from outside. And kidney problems can also determine the amount of memantine one should take of! Lounging around on the ACT ), may play a role in the development of anxiety memantine anxiety reddit has... Condition you are treating are key determinants and said he got a,! In this medication guide manny texted the group and said he got a raise, and I think 'm! And evening relevant reduction in anxiety symptoms when compared to baseline limit other antagonists... Reliant on a prescription medication she then told me how smart I was able to to! They do the trick for, it 's like having generalized anxiety disorder namenda a... ( range 5-20 mg/d ) the bed even the common side effects from memantine has. Range that ’ s honestly one of my favorite substances just because of functional. Been found to enter the brain to stimulate GABA production and modestly glutamate... The Amen Clinics ' categorizations and safety profile in pregnancy might give memantine an advantage over other antimigraine medications dissociative... Might be a tolerable and efficacious option for prophylaxis in patients with migraine without aura could... Allowed to post a source in tech actually had a great conversation regarding AI, programming, our futures etc...